YC Summer 2026 (S26) company

Aerogen Systems

Building the future of advanced chip manufacturing.

About Aerogen Systems

We are building the future of chip manufacturing. Chips are more advanced than ever, and the features inside them keep getting smaller. But the cleanroom infrastructure supporting their manufacture has not scaled at the same pace. Intel, TSMC, Samsung, and others spend billions building and operating massive cleanrooms, only to isolate their most advanced wafers from the surrounding facility as much as possible. We think that architecture is backwards. Instead of making the entire building cleaner, why not make the machinery itself as clean as possible? Talos is our proprietary tool-integrated purification system. It sits directly inside semiconductor equipment and continuously destroys airborne molecular contaminants before they reach the wafer. Instead of fighting contamination by constantly flooding tools with ultra-high-purity nitrogen, Talos keeps the environment inside the machine 10–100x cleaner, without the massive purge-gas bill. Talos is powerful on its own, but it is also the foundation for a much bigger vision: the Cleanpipe. The Aerogen Systems Cleanpipe is an ultra-clean interconnect infrastructure that protects wafers as they move from machine to machine across the fab. Rather than relying on a billion-dollar cleanroom to protect every cubic foot of factory space, Cleanpipe creates a controlled environment only where cleanliness actually matters: around the wafer. Talos cleans the tools. Cleanpipe connects them. Eventually, we delete the cleanroom and build more advanced chips, at greater scale, with radically less infrastructure. With cleanpipes connecting tools, chip fabs can exist anywhere.

Public traction evidence

Each signal links to the public source used for attribution.

  1. X

    We’re launching Aerogen Systems on YC today.

    We’re launching Aerogen Systems on YC today. We put modular reactor purifiers inside chipmaking tools to keep wafers clean without a cleanroom. Talos cleans the tools. The Cleanpipe connects them. Find us here: https://t.co/MjavehU0Md

  2. LinkedIn

    We're honored to be featured by the University of Michigan Center for Entrepreneurship (CFE) and grateful to receive support from the Fuel program! Aerogen Systems is turning a campus project into deployable VOC destruction tech. Built for sustainability, uptime, and real-world impact. Excited for what’s next! Special thanks to Alison Smith, MSE, Eric Bacyinski, John Woods, and Roger Van Duinen for their support during and post-competition. …more

    We're honored to be featured by the University of Michigan Center for Entrepreneurship (CFE) and grateful to receive support from the Fuel program! Aerogen Systems is turning a campus project into deployable VOC destruction tech. Built for sustainability, uptime, and real-world...

  3. LinkedIn

    (YC S26) just joined Y Combinator 🚀 We're building for one of the most expensive problems in chip manufacturing: contamination control at the tool level. As transistors approach atomic scales, manufacturing processes get brutally sensitive to Airborne Molecular Contamination (AMC). We build systems that destroy contamination directly in the tool, working quietly in the background of a fab to claw back massive yield loss that's currently left on the table while slashing ultra-high purity Nitrogen purge budgets. The need for a tool-integrated, reliable contamination control solution could not be more timely, with demand for advanced chips being higher than it’s ever been before. If we can’t figure out how to scale manufacturing and retain yield for the next generation of advanced nodes, we can't build the best processors, memory chips, and GPUs the world needs. None of this happens withou

    (YC S26) just joined Y Combinator 🚀 We're building for one of the most expensive problems in chip manufacturing: contamination control at the tool level. As transistors approach atomic scales, manufacturing processes get brutally sensitive to Airborne Molecular Contamination...

  4. LinkedIn

    Innovation is a two-way street. That was my biggest takeaway from a great week at the SEMI Americas Strategic Materials Conference. Colin Lavery and I came to learn more about semiconductor materials and manufacturing, and left full of new ideas, relationships, and even more conviction about where the industry is headed. One insight that stuck with me came from an early talk on advanced packaging (and was reinforced in conversations afterward): molecular contamination is becoming a major bottleneck, especially as advanced packaging and hybrid bonding push manufacturing to new limits. The need for better contamination control has never been clearer. It reinforced our belief that Aerogen Systems (YC S26)'s approach to tool-integrated contamination control is addressing one of the industry's most pressing challenges. My biggest takeaway, though, came from the closing executive panel. Repres

    Innovation is a two-way street. That was my biggest takeaway from a great week at the SEMI Americas Strategic Materials Conference. Colin Lavery and I came to learn more about semiconductor materials and manufacturing, and left full of new ideas, relationships, and even more...

  5. LinkedIn

    (YC S26) builds modular reactors that destroy contaminants in chip fabs, keeping wafers clean without a cleanroom. Chip features keep getting smaller, but cleanroom infrastructure does not scale with them. Semiconductor manufacturers spend billions building and operating enormous cleanrooms, then spend even more isolating their most advanced wafers from the surrounding environment. At leading-edge nodes, trace airborne contaminants can create defects, reduce yield, and disrupt some of the most sensitive manufacturing processes on Earth. But the whole factory does not need to be a cleanroom. Only the environment immediately surrounding the wafer does. The Aerogen Systems’ purification unit, Talos, integrates directly into semiconductor equipment and continuously destroys airborne molecular contaminants before they reach the wafer. Instead of relying on constant ultra-high-purity nitrogen

    (YC S26) builds modular reactors that destroy contaminants in chip fabs, keeping wafers clean without a cleanroom. Chip features keep getting smaller, but cleanroom infrastructure does not scale with them. Semiconductor manufacturers spend billions building and operating...

  6. YouTube

    Aerogen Systems

    Building the future of semiconductor manufacturing.