YC Spring 2026 (P26) company

Astraea

AI Operating System for Clinical Development

b2bb2b8 public signals

About Astraea

Astraea automates clinical trial biometrics from raw study inputs to FDA-ready outputs. The platform handles data normalization, CDISC mapping, SDTM, ADaM, TFLs, QC, and revision workflows in one auditable system, helping Phase II/III sponsors reduce months of manual programming and data management into automated, reviewable execution.

Public traction evidence

Each signal links to the public source used for attribution.

  1. X

    I’ve burned through 30.2B GPT-5.5 tokens in the last 2 months on Astraea. At public pricing, that’s roughly $30k-$225k+ of equivalent API usage depending on cache/output mix. My cost: 800 bucks. Lesson learned: Token maxxing > token saving. Cheap runs that fail aren’t Show more

    I’ve burned through 30.2B GPT-5.5 tokens in the last 2 months on Astraea. At public pricing, that’s roughly $30k-$225k+ of equivalent API usage depending on cache/output mix. My cost: 800 bucks. Lesson learned: Token maxxing > token saving. Cheap runs that fail aren’t Show more

  2. X

    Astraea just launched on @ycombinator's Launch YC!

    Astraea just launched on @ycombinator's Launch YC!

  3. X

    Replacing legacy pharma pipeline inefficiency

    Most pharma companies spend 6-8 months on SDTM and ADaM. That's not rigor. That's legacy pipeline inefficiency. The data hasn't changed. Only the tools have.

  4. X

    One clinical data pipeline and source of truth

    Every clinical data manager I talk to says the same thing: 'We have 12 tools and none of them talk to each other.' One pipeline. One source of truth. That's what Astraea is.

  5. X

    Automation with accountability at Astraea

    We hear 'AI in pharma is risky' constantly. We agree. That's why every Astraea output is reviewed by a human before it moves downstream. Automation with accountability.

  6. X

    CDISC compliance is table stakes. The real differentiator is how fast you can iterate after a regulatory query. Astraea lets you regenerate and resubmit in hours, not weeks.

    CDISC compliance is table stakes. The real differentiator is how fast you can iterate after a regulatory query. Astraea lets you regenerate and resubmit in hours, not weeks.

  7. X

    Removing repetitive manual steps from TLF generation

    The difference between 6 months and 1 week for TLF generation isn't about cutting corners. It's about removing repetitive manual steps that add zero statistical value.

  8. X

    Ask your biostatistics programmers what they'd do with five extra months

    Ask your biostatistics programmers what they'd do with 5 extra months per submission. Then show them Astraea.