Gamgee
Curing cancer. Starting with dogs.
About Gamgee
Gamgee began with Rosie, founder Paul Conyngham’s dog. After surgery, chemotherapy and immunotherapy failed, Rosie was given months to live. Paul used AI and genomic analysis to identify targets in her tumour, then worked with scientists at UNSW to produce what is believed to be the first fully computationally designed mRNA cancer vaccine delivered to a dog. Following treatment, several tumours shrank significantly and her quality of life improved Gamgee is building an end to end platform for personalised mRNA cancer vaccines for dogs. We sequence a dog’s tumour and healthy DNA, identify mutations unique to its cancer, and design a vaccine that teaches the immune system what to attack. We manage the entire process- from vet intake and tissue collection through genomic analysis, vaccine production, treatment and response monitoring We are now turning that one off effort into a repeatable clinical system. Gamgee is running clinical trials in Australia, working with vets, oncologists and specialised laboratories, and accepting cases globally. Our goal is to make personalised cancer treatment accessible to every dog that needs it- and use each case to improve the treatment for the next
Public traction evidence
Each signal links to the public source used for attribution.
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How I created Rosie's mRNA Vaccine Protocol Everyone asks me how I did it.
How I created Rosie's mRNA Vaccine Protocol Everyone asks me how I did it. Here it is Part 1: Rosie's Story June 2023: About three years ago, I noticed something wrong with Rosie. She had swollen lumps on her head and leg, and it was
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I lost my dog because we could not build her next mRNA cancer vaccine fast enough Today we are announcing a $4M seed led by @foundersfund to change that.
I lost my dog because we could not build her next mRNA cancer vaccine fast enough Today we are announcing a $4M seed led by @foundersfund to change that.
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My dog Rosie was given months to live.
My dog Rosie was given months to live. Chemo and immunotherapy failed I used chatgpt + computational genomics to design a personalised mRNA cancer vaccine for her tumour. Several of her tumours shrank Today we launch Gamgee (YC S26): personalised mRNA cancer vaccines for dogs...
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proud to be in this summers YC batch to scale the work i did for Rose https://t.co/Q9b4CL4aNF
proud to be in this summers YC batch to scale the work i did for Rose https://t.co/Q9b4CL4aNF
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i am scaling the work i did for Rose through a company today we launch Gamgee: software to design personalised cancer treatments for dogs https://t.co/Kg1HizqOpF
i am scaling the work i did for Rose through a company today we launch Gamgee: software to design personalised cancer treatments for dogs https://t.co/Kg1HizqOpF
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Our S26 @ycombinator batchmates did most of the heavy lifting on our launch video.
Our S26 @ycombinator batchmates did most of the heavy lifting on our launch video. Cost $2.5k. Bargain These are the folks building bite-sized anime microdramas (2-min episodes, new ones daily). Ridiculously talented crew It was extremely fun working with @_nobi_obi to make
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haters going to hate the main controversy around the protocol Rosie received was that her mRNA vaccine was paired with a pd-1 inhibitor today Moderna and Merck reported positive phase 3 results in human melanoma for intismeran, their personalised mRNA cancer vaccine, combined
haters going to hate the main controversy around the protocol Rosie received was that her mRNA vaccine was paired with a pd-1 inhibitor today Moderna and Merck reported positive phase 3 results in human melanoma for intismeran, their personalised mRNA cancer vaccine, combined
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two people sending software patches down to biology.
two people sending software patches down to biology. absolute pleasure @bryan_johnson https://t.co/9GWx5e8e5k